Tag: toxins
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Mitochondrial Dysfunction and Type 2 Diabetes: Mechanisms, Markers, and Interventions
Type 2 diabetes can be assessed from the perspective of mitochondrial dysfunction as not just a side effect, but a factor in its progression. Symptoms like fatigue and difficulty concentrating can be a sign that mitochondria aren’t functioning properly, and that same underlying dysfunction may be feeding the disease process itself. When mitochondria are impaired,…
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Glucuronidation and Enterohepatic Recirculation
β-glucuronidase produced by the microbiome can deconjugate xenobiotics that have already undergone glucuronidation by phase II enzymes, causing them to undergo enterohepatic recirculation rather than being eliminated in the feces. Elmassry et al. (2021) found that males have higher levels of intestinal β-glucuronidase than females, and infants have higher levels than their mothers. Malik et…
Northern Nutritionals 