Tag: toxins
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Glucuronidation and Enterohepatic Recirculation
β-glucuronidase produced by the microbiome can deconjugate xenobiotics that have already undergone glucuronidation by phase II enzymes, causing them to undergo enterohepatic recirculation rather than being eliminated in the feces. Elmassry et al. (2021) found that males have higher levels of intestinal β-glucuronidase than females, and infants have higher levels than their mothers. Malik et…
