Tag: probiotics
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Inflammation, Alcohol, and Pain
Pain is, at its core, a signal of inflammation. Understanding how the immune system generates that inflammation — and how alcohol use specifically adds fuel to the fire — makes it easier to understand how inflammation contributes to chronic pain, and what might help resolve that inflammation. How the Immune System Creates Inflammation When toll-like…
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Intestinal Permeability, Celiac Disease, and Tight Junctions
Intestinal permeability — how easily substances pass through the intestinal barrier rather than being kept out — plays a central role in celiac disease and gluten sensitivity. Remission Can Mean a Return to Normal Barrier Function Hollon et al. (2015) exposed intestinal biopsy specimens to gliadin and measured the resulting change in permeability across several…
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Nightshade Sensitivity: The Immune Mechanism, and Interventions
Some people experience joint pain as an inflammatory reaction to nightshades like tomatoes and peppers. Understanding the immune pathway behind that reaction — and what separates a reactive response from a tolerant one — points toward some practical places to intervene. The Immune Pathway Behind Nightshade Sensitivity Nightshade proteins are transported across intestinal microfold cells,…
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Malabsorption
Even if someone’s diet seems to include plenty of a particular nutrient, if they aren’t absorbing the nutrients they are consuming they could still have deficiencies. In the Discussion section of their paper, the authors of the LIFEHOUSE study (Stone et al., 2023) mention vertical ridging of the nails as an example of a symptom…
