Tag: microbiome
-
Nightshade Sensitivity: The Immune Mechanism, and Interventions
Some people experience joint pain as an inflammatory reaction to nightshades like tomatoes and peppers. Understanding the immune pathway behind that reaction — and what separates a reactive response from a tolerant one — points toward some practical places to intervene. The Immune Pathway Behind Nightshade Sensitivity Nightshade proteins are transported across intestinal microfold cells,…
-
Supporting Mitochondrial Health: Urolithin A and Light Therapy
Two very different interventions — a gut-microbiome-derived postbiotic and a light-based therapy — offer an interesting look at how mitochondrial function can be supported through different mechanisms: clearing out damaged mitochondria on one hand, and directly powering the electron transport chain on the other. Urolithin A Singh et al. (2022) ran a randomized, double-blind, placebo-controlled…
-
Malabsorption
Even if someone’s diet seems to include plenty of a particular nutrient, if they aren’t absorbing the nutrients they are consuming they could still have deficiencies. In the Discussion section of their paper, the authors of the LIFEHOUSE study (Stone et al., 2023) mention vertical ridging of the nails as an example of a symptom…
-
Artificial Sweeteners, Microbiome, and Glucose Tolerance
Some studies (Ahmad et al., 2020; Serrano et al., 2021) have concluded that consumption pf normal amounts of artificial sweeteners such as aspartame, saccharin, or sucralose, does not impact the gastrointestinal microbiota. However, Suez et al. (2014) found the correlation between non-caloric artificial sweetener intake and Enterbacteriaceae, Deltaproteobacteria, and Actinobacteria to be statistically significant, when…
-
Polyphenols for Intestinal Permeability
Del Bo’ et al. (2021) conducted a randomized controlled trial to see if a diet emphasizing polyphenols would be able to help address intestinal permeability in older people. They found that beneficial bacteria for fiber fermentation and butyrate were increased, and blood pressure was decreased. Those who started out with greater impairment of the tight…
-
Microbiome of Depression
Szabo de Edelenyi et al. (2021) wanted to begin testing the hypothesis that eating more fruits and vegetables would lower the amount of indole produced by gastrointestinal bacteria, resulting in a reduced risk for depression. They selected a sample of 2,054 women ages 45-65 from within the participants of a larger prospective cohort study called…
