Tag: insulin resistance
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Mitochondrial Dysfunction and Type 2 Diabetes: Mechanisms, Markers, and Interventions
Type 2 diabetes can be assessed from the perspective of mitochondrial dysfunction as not just a side effect, but a factor in its progression. Symptoms like fatigue and difficulty concentrating can be a sign that mitochondria aren’t functioning properly, and that same underlying dysfunction may be feeding the disease process itself. When mitochondria are impaired,…
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Two Manifestations of Oxidative Stress: Cataracts and Steatotic Liver Disease
The following two examples — one on age-related cataracts, and one on Steatotic Liver Disease (SLD) — both illustrate how cells try to compensate for oxidative stress, and what happens when those compensatory systems eventually fail. Oxidative Stress and Cataract Formation Huang et al. (2022) investigated how biliverdin reductase A protects lens epithelial cells from…
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Polyphenols for Intestinal Permeability
Del Bo’ et al. (2021) conducted a randomized controlled trial to see if a diet emphasizing polyphenols would be able to help address intestinal permeability in older people. They found that beneficial bacteria for fiber fermentation and butyrate were increased, and blood pressure was decreased. Those who started out with greater impairment of the tight…
Northern Nutritionals 