Tag: estrogen

  • Glucuronidation and Enterohepatic Recirculation

    β-glucuronidase produced by the microbiome can deconjugate xenobiotics that have already undergone glucuronidation by phase II enzymes, causing them to undergo enterohepatic recirculation rather than being eliminated in the feces.   Elmassry et al. (2021) found that males have higher levels of intestinal β-glucuronidase than females, and infants have higher levels than their mothers.  Malik et…

  • Protein, Brassicas, and Dietary Fiber

    I found an interesting study where glutathione was found to decrease after participants spent three days on a lower protein diet than what they were used to, but it appeared to return to normal by day ten (Jackson et al., 2004).   Eating brassicas could help the estrogen metabolizing pathways to lead to less of…