Tag: endotoxins
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Inflammation, Alcohol, and Pain
Pain is, at its core, a signal of inflammation. Understanding how the immune system generates that inflammation — and how alcohol use specifically adds fuel to the fire — makes it easier to understand how inflammation contributes to chronic pain, and what might help resolve that inflammation. How the Immune System Creates Inflammation When toll-like…
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Yoga and Immune Balance
Regulatory T cells (Tregs) are central to immune tolerance, and it turns out a daily yoga practice is one way to support them. That finding — along with ideas about cytokines and immune balance — is central to my thinking on lifestyle recommendations. Yoga and the Treg/Th17 Balance in Rheumatoid Arthritis Gautam et al. (2023)…
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St, John’s Wort and CYP450 Pathways
Dürr et al. (2000) gave 300 mg of St. John’s Wort to healthy volunteers three times a day for two weeks. They found that this induced CYP3A4 in both the liver and the intestines, which explained the interactions that had been observed between St. John’s wort and certain drugs. It seems that it reduced the…
